Of all the cities in the United States, it's hard to find a better mancation or guys weekend destination than New Orleans. The Big Easy – which deserves its nickname, by the way – boasts some of the best restaurants, music clubs and bars in the world, all in a fun, eccentric, party atmosphere.
Guys who like fishing and golf will be amazed at the opportunities for outdoor recreation during the day. There's so much to do, you and your buddies might have to make the New Orleans trip an annual ritual.